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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AAK1
All Species:
8.48
Human Site:
T448
Identified Species:
26.67
UniProt:
Q2M2I8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M2I8
NP_055726.3
863
93578
T448
T
P
Q
Q
T
P
S
T
Q
A
Q
G
L
P
A
Chimpanzee
Pan troglodytes
XP_001138187
865
93810
T448
T
P
Q
Q
T
P
S
T
Q
A
Q
G
L
P
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531855
473
51892
I111
V
G
Y
I
D
S
S
I
N
N
V
S
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHJ0
959
103328
T448
T
P
Q
Q
T
P
A
T
Q
T
Q
G
L
P
T
Rat
Rattus norvegicus
P0C1X8
962
103742
P447
T
P
Q
Q
T
P
A
P
Q
T
Q
G
L
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417663
953
102927
Q448
P
Q
Q
A
S
Q
A
Q
P
Q
V
P
S
A
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625109
598
65629
L236
L
G
C
L
L
Y
K
L
C
F
F
T
L
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40494
810
91014
F432
T
F
K
S
V
E
S
F
Q
S
P
Q
R
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
53.7
N.A.
80.7
79.9
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
54.4
N.A.
83.1
82.7
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
80
73.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
6.6
N.A.
86.6
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
38
0
0
25
0
0
0
13
25
% A
% Cys:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
13
0
13
13
0
0
0
13
% F
% Gly:
0
25
0
0
0
0
0
0
0
0
0
50
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
13
0
0
0
0
0
0
13
0
% K
% Leu:
13
0
0
13
13
0
0
13
0
0
0
0
63
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% N
% Pro:
13
50
0
0
0
50
0
13
13
0
13
13
0
63
0
% P
% Gln:
0
13
63
50
0
13
0
13
63
13
50
13
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
0
0
13
13
13
50
0
0
13
0
13
25
0
13
% S
% Thr:
63
0
0
0
50
0
0
38
0
25
0
13
0
0
25
% T
% Val:
13
0
0
0
13
0
0
0
0
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _